Age-associated changes in hypothalamic-pituitary-testicular function in middle-aged and older men are modified by weight change and lifestyle factors: longitudinal results from the European Male Ageing Study
Camacho, E M × Huhtaniemi, I T O'Neill, T W Finn, J D Pye, S R Lee, D M Tajar, A Bartfai, G Boonen, Steven Casanueva, F F Forti, G Giwercman, A Han, T S Kula, K Keevil, B Lean, M E Pendleton, N Punab, M Vanderschueren, Dirk Wu, F C W EMAS Group #
European Journal of Endocrinology vol:168 issue:3 pages:445-55
Health and lifestyle factors are associated with variations in serum testosterone levels in ageing men. However, it remains unclear how age-related changes in testosterone may be attenuated by lifestyle modifications. The objective was to investigate the longitudinal relationships between changes in health and lifestyle factors with changes in hormones of the reproductive endocrine axis in ageing men.