Title: Evidence of possible methicillin-resistant Staphylococcus aureus ST398 spread between pigs and other animals and people residing on the same farm
Authors: Pletinckx, Larissa ×
Verhegghe, Marijke
Crombé, Florence
Dewulf, Jeroen
De Bleecker, Yves
Rasschaert, Geertrui
Butaye, Patrick
Goddeeris, Bruno
De Man, Ingrid #
Issue Date: 2013
Publisher: Elsevier Scientific Pub. Co.
Series Title: Preventive Veterinary Medicine vol:109 pages:293-303
Article number: S0167-5877(12)00374-1
Abstract: Methicillin-resistant Staphylococcus aureus (MRSA) has emerged in a wide variety of animal species. However, little is known about the transmission routes of MRSA ST398 between different animal species, the barn environment and people residing on the same farm. In this study, two pig farms, two poultry-pig and two dairy-pig farms were investigated with respect to the presence of MRSA. On each farm, samples were collected from all animal species present, the barn environment, the farmer, household members and the herd veterinarians. Besides the MRSA prevalence, the obtained spa-, SCCmec-type and antimicrobial susceptibility profiles were also compared. Multilocus sequence typing (MLST) showed that MRSA ST398 was found in all animal species, in humans present on the farms and also in the pig barn environment. The presence of MRSA with the same spa-, SCCmec-type and antibiotic profile in the different animal species in direct or indirect contact with pigs suggests MRSA transfer. Furthermore, different pig age categories were investigated, with weaned piglets having the highest MRSA prevalence (86.3%). The herd-level prevalence was highly correlated (r=0.86, p=0.03) between sows and pre-weaned piglets. The results also indicate that companion animals, rats, mice and farmers could play an important role in the dissemination of MRSA, emphasizing the importance of internal biosecurity. However, external biosecurity is equally important because other spa-, SCCmec-types or antimicrobial resistances can be introduced through purchase of gilts. In this study we demonstrated that MRSA likely spreads between animal species, humans and the pig barn environment, which is why it is important to accurately implement control practices, in which not only pigs should be targeted, but also all other animal species present on farms.
ISSN: 0167-5877
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Division of Gene Technology (-)
Studiegebied Gezondheidszorg VIVES-Zuid
× corresponding author
# (joint) last author

Files in This Item:
File Description Status SizeFormat
Pletinckx 2013 Prev Vet Med.pdf Published 414KbAdobe PDFView/Open Request a copy

These files are only available to some KU Leuven Association staff members


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science