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Title: Influence of preoperative and postoperative pelvic floor muslce training (PFMT) compared with postoperative PFMT on urinary incontinence after radical prostatectomy: a randomized controlled trial
Authors: Geraerts, Inge ×
Van Poppel, Hendrik
Devoogdt, Nele
Joniau, Steven
Van Cleynenbreugel, Ben
De Groef, An
Van Kampen, Marijke #
Issue Date: 2013
Publisher: Elsevier Science
Series Title: European Urology vol:64 issue:5 pages:766-772
Conference: annual EAU congress edition:28 location:Milan date:15-19 March
Abstract: Influence of Preoperative and Postoperative Pelvic Floor Muscle Training (PFMT) Compared with Postoperative PFMT on Urinary Incontinence After Radical Prostatectomy: A Randomized Controlled Trial.
Geraerts I, Van Poppel H, Devoogdt N, Joniau S, Van Cleynenbreugel B, De Groef A, Van Kampen M.
SourceKU Leuven, Department of Rehabilitation Science, Leuven, Belgium. Electronic address: inge.geraerts@faber.kuleuven.be.

Abstract
BACKGROUND: The efficacy of preoperative pelvic floor muscle training (PFMT) for urinary incontinence (UI) after open radical prostatectomy (ORP) and robot-assisted laparoscopic radical prostatectomy (RARP) is still unclear.

OBJECTIVE: To determine whether patients with additional preoperative PFMT regain urinary continence earlier than patients with only postoperative PFMT after ORP and RARP.

DESIGN, SETTING, AND PARTICIPANTS: A randomized controlled trial enrolled 180 men who planned to undergo ORP/RARP.

INTERVENTION: The experimental group (E, n=91) started PFMT 3 wk before surgery and continued after surgery. The control group (C, n=89) started PFMT after catheter removal.

OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: The primary end point was time to continence. Patients measured urine loss daily (24-h pad test) until total continence (three consecutive days of 0g of urine loss) was achieved. Secondary end points were 1-h pad test, visual analog scale (VAS), International Prostate Symptom Score (IPSS), and quality of life (King's Health Questionnaire [KHQ]). Kaplan-Meier analysis and Cox regression with correction for two strata (age and type of surgery) compared time and continence. The Fisher exact test was applied for the 1-h pad test and VAS; the Mann-Whitney U test was applied for IPSS and KHQ.

RESULTS AND LIMITATIONS: Patients with additional preoperative PFMT had no shorter duration of postoperative UI compared with patients with only postoperative PFMT (p=0.878). Median time to continence was 30 and 31 d, and median amount of first-day incontinence was 108g and 124g for groups E and C, respectively. Cox regression did not indicate a significant difference between groups E and C (p=0.773; hazard ratio: 1.047 [0.768-1.425]). The 1-h pad test, VAS, and IPSS were comparable between both groups. However, "incontinence impact" (KHQ) was in favor of group E at 3 mo and 6 mo after surgery.

CONCLUSIONS: Three preoperative sessions of PFMT did not improve postoperative duration of incontinence.

TRIAL REGISTRATION: Netherlands Trial Register No. NTR 1953.
ISSN: 0302-2838
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Research Group for Neuromotor Rehabilitation
Screening, Diagnostics and Biomarkers (-)
Research Group for Cardiovascular and Respiratory Rehabilitation
Department of Health and Technology - UC Leuven
× corresponding author
# (joint) last author

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