Title: Lysogenic Conversion and Phage Resistance Development in Phage Exposed Escherichia coli Biofilms
Authors: Moons, Pieter
Faster, David
Aertsen, Abram # ×
Issue Date: 2013
Publisher: Molecular Diversity Preservation International
Series Title: Viruses vol:5 issue:1 pages:150-161
Abstract: In this study, three-day old mature biofilms of Escherichia coli were exposed once to either a temperate Shiga-toxin encoding phage (H-19B) or an obligatory lytic phage (T7), after which further dynamics in the biofilm were monitored. As such, it was found that a single dose of H-19B could rapidly lead to a near complete lysogenization of the biofilm, with a subsequent continuous release of infectious H-19B particles. On the other hand, a single dose of T7 rapidly led to resistance development in the biofilm population. Together, our data indicates a profound impact of phages on the dynamics within structured bacterial populations.
ISSN: 1999-4915
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Centre for Food and Microbial Technology
× corresponding author
# (joint) last author

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