Title: Diabetic gastroparesis
Authors: Vanormelingen, Christophe ×
Tack, Jan
Andrews, Christopher N #
Issue Date: 2013
Publisher: Royal Society of Medicine Press
Series Title: British medical bulletin vol:105 pages:213-30
Abstract: BackgroundDiabetic gastroparesis (DGP) is a gastric complication of diabetes mellitus that causes nausea, vomiting, early satiety, bloating and abdominal pain, in addition to significant morbidity.Sources of dataOriginal and review articles were reviewed through PubMed, including relevant guidelines from the European and American Neurogastroenterology Societies.Areas of agreementDiagnosis of DGP requires endoscopy and measurement of gastric emptying. Management requires prokinetic therapy, usually in addition to antinausea or other medications.Areas of controversyThe pathogenesis of DGP is poorly understood. Management strategies are highly variable.Growing pointsProkinetic and neuromodulatory medications are in human clinical trials specifically for gastroparesis.Areas timely for developing researchFurther understanding of the molecular pathology leading to DGP is required to potentially arrest the development of this serious diabetic complication. Evaluation of novel agents for use in DGP is sorely needed.
ISSN: 0007-1420
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Research in GastroIntestinal Disorders
× corresponding author
# (joint) last author

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