Displacement affinity chromatography of protein phosphatase one (PP1) complexes
Moorhead, Greg B G × Trinkle-Mulcahy, Laura Nimick, Mhairi De Wever, Veerle Campbell, David G Gourlay, Robert Lam, Yun Wah Lamond, Angus I #
BMC Biochemistry vol:9 pages:28
Protein phosphatase one (PP1) is a ubiquitously expressed, highly conserved protein phosphatase that dephosphorylates target protein serine and threonine residues. PP1 is localized to its site of action by interacting with targeting or regulatory proteins, a majority of which contains a primary docking site referred to as the RVXF/W motif.