Title: Involvement of neb-colloostatin, a collagen-related peptide, in early vitellogenesis of the grey fleshfly
Authors: Bylemans, Dany ×
Proost, Paul
Samyn, B
Van Beeumen, J
Van Damme, Jozef
De Loof, Arnold #
Issue Date: 1995
Publisher: Dutch assoc zoology
Series Title: Netherlands Journal of Zoology vol:45 issue:1-2 pages:172-174
Abstract: During the purification procedure of the first folliculostatin of the grey fleshfly Neobellieria bullata, the Trypsin-Modulating Oostatic Factor (Neb-TMOF), a second factor with oostatic activity, was discovered. Here we report the primary structure and effects on oocyte development of the latter factor. The amino acid sequence was determined as H-SIVPLGLPVPIGPIVVGPR-OH. Because of structural sequence similarities with parts of several known collagens and because of its oostatic activity, we named the factor Neb-colloostatin. The synthetic peptide inhibits yolk uptake by previtellogenic oocytes and might be the factor thai determines that per ovariole only one follicle develops at a time.
ISSN: 0028-2960
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Division of Crop Biotechnics
Laboratory of Molecular Immunology (Rega Institute)
Department of Biology - miscellaneous
× corresponding author
# (joint) last author

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