Title: Evidence for new phosphorylation sites for protein-kinase-c and cyclic amp-dependent protein-kinase in bovine heart 6-phosphofructo-2-kinase fructose-2,6-bisphosphatase
Authors: Rider, Mh
Vandamme, J
Vertommen, Didier
Michel, A
Van de Kerckhove, J
Hue, L #
Issue Date: 1992
Publisher: Elsevier science bv
Series Title: FEBS Letters vol:310 issue:2 pages:139-142
Abstract: Bovine heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) was phosphorylated by incubation with [gamma-P-32]MgATP and cyclic AMP-dependent protein kinase (PKA) or protein kinase C (PKC). After digestion with chymotrypsin, the phosphorylation sites for the two protein kinases were identified by peptide mapping, and microsequencing. Evidence for new phosphorylation sites for PKA (Ser-483) and PKC (Ser-84 and Ser-466) was obtained.
ISSN: 0014-5793
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Biochemistry Section (Medicine) (-)
# (joint) last author

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