Title: Design of a flow controlled asymmetric droplet splitter using computational fluid dynamics
Authors: Verbruggen, Bert
Tóth, Tamara
Atalay, Yegermal Tesfaw
Ceyssens, Frederik
Verboven, Pieter
Puers, Robert
Nicolai, Bart
Lammertyn, Jeroen # ×
Issue Date: 22-Jan-2013
Series Title: Microfluidics and Nanofluidics vol:15 issue:2 pages:243-252
Abstract: In this work the design of a segmented flow microfluidic device is presented that allows droplet splitting ratios from 1:1 up to 20:1. This ratio can be dynamically changed on chip by altering an additional oil flow. The design was fabricated in PDMS chips using the standard SU-8 mold technique and does not require any valves, membranes, optics or electronics. To avoid a trial and error approach, fabricating and testing several designs, a computational fluid dynamics (CFD) model was developed and validated for droplet formation and splitting. The model was used to choose between several variations of the splitting T-junction with the extra oil inlet, as well to predict the additional flow rate needed to split the droplets in various ratios. Experimental and simulated results were in line, suggesting the model’s suitability to optimize future designs and concepts. The resulting asymmetric droplet splitter design opens possibilities for controlled sampling and improved magnetic separation in bio-assay applications.
ISSN: 1613-4982
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Division of Mechatronics, Biostatistics and Sensors (MeBioS)
ESAT - MICAS, Microelectronics and Sensors
× corresponding author
# (joint) last author

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