Title: Selection and Characterization of a Candidate Therapeutic Bacteriophage That Lyses the Escherichia coli O104:H4 Strain from the 2011 Outbreak in Germany
Authors: Merabishvili, Maia
De Vos, Daniel
Verbeken, Gilbert
Kropinski, Andrew M
Vandenheuvel, Dieter
Lavigne, Rob
Wattiau, Pierre
Mast, Jan
Ragimbeau, Catherine
Mossong, Joel
Scheres, Jacques
Chanishvili, Nina
Vaneechoutte, Mario
Pirnay, Jean-Paul # ×
Issue Date: 2012
Publisher: Public Library of Sciene
Series Title: PLoS One vol:7 issue:12 pages:e52709
Article number: 10.1371/journal.pone.0052709
Abstract: In 2011, a novel strain of O104:H4 Escherichia coli caused a serious outbreak of foodborne hemolytic uremic syndrome and bloody diarrhea in Germany. Antibiotics were of questionable use and 54 deaths occurred. Candidate therapeutic bacteriophages that efficiently lyse the E. coli O104:H4 outbreak strain could be selected rather easily from a phage bank or isolated from the environment. It is argued that phage therapy should be more considered as a potential armament against the growing threat of (resistant) bacterial infections.
ISSN: 1932-6203
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Division of Gene Technology (-)
× corresponding author
# (joint) last author

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