Background: Health status self-reports are increasingly recognized as an important source of key follow-up data
after hematopoietic stem cell transplantation (HSCT).
Purpose: The purpose of this study was to evaluate the occurrence of self-reported symptoms and concerns in longterm
survivors and compare their prevalence’s between allogeneic and autologous transplant recipients with various
post-HSCT follow-up lengths.
Interventions/Methods: This cross-sectional survey included a convenience sample of 226 autologous and
allogeneic HSCT recipients (54% male; 1 to 26 (median 6) years post-transplant) treated as outpatients by the
multidisciplinary team of a Swiss stem cell transplant ambulatory. Symptoms and concerns were measured by a selfdeveloped
Results: The median number of self-reported physical symptoms per patient was 5(IQR 4-10), the most frequent
being dry skin (47.8%), tiredness (42%), and dry eyes (42%). The most commonly cited concerns were difficulties
managing stressful emotional situations (23.9%), anxiety regarding relapse (22.1%) and memory disturbance (21.2%).
There were no notable differences in appraisal of performance and number of symptoms between different time groups.
Conclusion: The high frequency of self-reported symptoms and concerns in long-term survivors indicates a need
for continuous monitoring by stem cell transplant follow up clinics, which would allow timely and effective interventions
to prevent or alleviate late effects.
Implications for Practice: There seems to be good opportunity for health professionals to support long-term
survivors by using self-report as clinical tool in follow-up care. Sharing information about problems and symptoms
patients face post-treatment will benefit both professionals and patients.