Title: Synthesis of 1-phosphono-2-aza-1,3-dienes and scope of their aziridination
Authors: Vanderhoydonck, B
Stevens, CV # ×
Issue Date: 2004
Publisher: Thieme Chemistry
Series Title: Synthesis issue:5 pages:722-734
Abstract: Several 1-phosphono-2-aza-1,3-dienes and 1-aryl-1-phosphono-2-aza-1,3-dienes were prepd. by 1,4-dehydrochlorination of the corresponding di-Et [(2-chloro-1-alkylidene)amino]methylphosphonates. 1-Phosphono-2-aza-1,3-dienes react smoothly with diazomethane to give 2-phosphono-1-vinylaziridines. The synthesis of 2-ethoxycarbonyl-3-phosphono-1-vinylaziridines was performed using Et diazoacetate (EDA) in the presence of ytterbium(III) triflate as a catalyst. 2-Phosphono-3-(trimethylsilyl)aziridines were prepd. from phosphonoazadienes by treatment with (trimethylsilyl)diazomethane under reflux. 1-Aryl-1-phosphono-2-aza-1,3-dienes are not susceptible to aziridination under these conditions.
ISSN: 0039-7881
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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