Title: Synthesis of (Z) and (E) a-alkenyl phosphonic acid derivatives of purines and pyrimidines
Authors: Lazrek, HB ×
Rochdi, A
Khaider, H
Barascut, JL
Imbach, J-L
Balzarini, Jan
Witvrouw, Myriam
De Clercq, Erik
Pannecouque, Christophe #
Issue Date: 1998
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron vol:54 issue:15 pages:3807-3816
Abstract: (Z) and (E)-2-(purin-9-yl/pyrimidin-1-yl)ethylen-1-ylphosphonic acid 10-18 were synthetized by Michael addition of heterocyclic base with the diethylethynylphosphonate and deprotection of the acyclic nucleoside phosphonate with bromotrimethylsilane. (C) 1998 Elsevier Science Ltd. All rights reserved.
ISSN: 0040-4020
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
Molecular Virology and Gene Therapy
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science