Title: A Diversity-Oriented Approach to Spiroindolines: Post-Ugi Gold-Catalyzed Diastereoselective Domino Cyclization
Authors: Modha, Sachin G ×
Kumar, Amit
Vachhani, Dipak
Jacobs, Jeroen
Sharma, Sunil
Parmar, Virinder
Van Meervelt, Luc
Van der Eycken, Erik #
Issue Date: Sep-2012
Publisher: Wiley-VCH
Series Title: Angewandte Chemie - International Edition vol:51 issue:38 pages:9572-9575
Abstract: Caught "Spiro" handed: A diversity-oriented approach comprised of an Ugi four-component reaction and a diastereoselective gold(I)-catalyzed domino cyclization for the generation of complex spiroindolines under mild conditions has been developed. Variously substituted spiroindolines were synthesized in good to excellent yields and with complete diastereoselectivity.
ISSN: 1433-7851
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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