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Title: BMI-related metabolic composition of the follicular fluid of women undergoing assisted reproductive treatment and the consequences for oocyte and embryo quality
Authors: Valckx, S D M ×
De Pauw, I
De Neubourg, Diane
Inion, I
Berth, M
Fransen, E
Bols, P E J
Leroy, J L M R #
Issue Date: Dec-2012
Publisher: Published for the European Society of Human Reproduction and Embryology by IRL Press
Series Title: Human Reproduction vol:27 issue:12 pages:3531-3539
Abstract: Is the metabolic composition of the follicular fluid of women undergoing assisted reproductive treatment (ART) related to serum composition and BMI and is it associated with oocyte and embryo quality? SUMMARY ANSWER: We showed that metabolic alterations in the serum are reflected in the follicular fluid and that some of these alterations may affect oocyte quality, irrespective of BMI. WHAT IS KNOWN ALREADY: Many studies have focused on the effect of metabolic disorders, such as obesity and type 2 diabetes, on assisted reproduction outcomes. There are, however, only few studies focusing on the importance of the correlation between serum and follicular fluid compositions and the composition of the follicular fluid as the oocyte's micro-environment, affecting its development and subsequent embryo quality.
URI: 
ISSN: 0268-1161
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Sexual, Pelvic, Reproductive and Family Studies (-)
× corresponding author
# (joint) last author

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