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Title: Ultrabithorax function in butterfly wings and the evolution of insect wing patterns
Authors: Weatherbee, S D
Nijhout, H F
Grunert, L W
Halder, Georg
Galant, R
Selegue, J
Carroll, S # ×
Issue Date: Feb-1999
Publisher: Current Biology Ltd.
Series Title: Current Biology vol:9 issue:3 pages:109-15
Abstract: . The morphological and functional evolution of appendages has played a critical role in animal evolution, but the developmental genetic mechanisms underlying appendage diversity are not understood. Given that homologous appendage development is controlled by the same Hox gene in different organisms, and that Hox genes are transcription factors, diversity may evolve from changes in the regulation of Hox target genes. Two impediments to understanding the role of Hox genes in morphological evolution have been the limited number of organisms in which Hox gene function can be studied and the paucity of known Hox-regulated target genes. We have therefore analyzed a butterfly homeotic mutant 'Hindsight', in which portions of the ventral hindwing pattern are transformed to ventral forewing identity, and we have compared the regulation of target genes by the Ultrabithorax (Ubx) gene product in Lepidopteran and Dipteran hindwings.
URI: 
ISSN: 0960-9822
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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