Title: Synthesis of fluorescent ristocetin aglycon derivatives with remarkable antibacterial and antiviral activities
Authors: Sipos, Attila ×
Máté, Gábor
Rőth, Erzsébet
Borbás, Anikó
Batta, Gyula
Bereczki, Ilona
Kéki, Sándor
Jóna, István
Ostorházi, Eszter
Rozgonyi, Ferenc
Vanderlinden, Evelien
Naesens, Lieve
Herczegh, Pál #
Issue Date: Dec-2012
Series Title: European Journal of Medicinal Chemistry vol:58 pages:361-367
Article number: S0223-5234(12)00634-4
Abstract: Isoindole and benzoisoindole derivatives of ristocetin aglycon have been prepared by reaction with o-phthalaldehyde or naphthalene-2,3-dialdehyde and various thiols. The new compounds exhibited potent antibacterial and anti-influenza virus activity. The cluster forming and fluorescent properties of the aglycon derivatives were also studied.
ISSN: 0223-5234
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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