Halpin, David Mg × Decramer, Marc Celli, Bartolome Kesten, Steven Liu, Dacheng Tashkin, Donald P #
DOVE Medical Press
International Journal of Chronic Obstructive Pulmonary Disease vol:7 pages:653-61
Exacerbations affect morbidity in chronic obstructive pulmonary disease (COPD). We sought to evaluate the association between exacerbation frequency and spirometric and health status changes over time using data from a large, long-term trial.