Enzymatic vitreolysis with ocriplasmin for vitreomacular traction and macular holes
Stalmans, Peter Benz, Matthew S Gandorfer, Arnd Kampik, Anselm Girach, Aniz Pakola, Stephen Haller, Julia A × MIVI-TRUST Study Group #
New England Journal of Medicine vol:367 issue:7 pages:606-615
Vitreomacular adhesion can lead to pathologic traction and macular hole. The standard treatment for severe, symptomatic vitreomacular adhesion is vitrectomy. Ocriplasmin is a recombinant protease with activity against fibronectin and laminin, components of the vitreoretinal interface.