W.B. Saunders for the American Gastroenterological Association
Clinical Gastroenterology and Hepatology vol:10 issue:11 pages:1239-1245
Impaired accommodation and hypersensitivity to gastric distention are believed to be involved in the development of functional dyspepsia (FD). Buspirone, a 5-hydroxytryptamine 1A receptor agonist, relaxes the proximal stomach in healthy individuals. We studied the effects of buspirone on symptoms and mechanisms of FD.