Title: Characterization of a dorsal-eye Gal4 Line in Drosophila
Authors: Morrison, Clayton M
Halder, Georg # ×
Issue Date: Jan-2010
Publisher: John Wiley & Sons, Inc.
Series Title: Genesis: The Journal of Genetics and Development vol:48 issue:1 pages:3-7
Abstract: In Drosophila, the Gal4-UAS system is used to drive ectopic gene expression in a tissue-specific manner. In this system, transgenic flies expressing tissue specific Gal4 are crossed to a line in which the gene to be expressed is under the control of a Gal4-responsive UAS sequence. The resulting progeny express the gene of interest in the pattern of the particular Gal4 line. Since a given UAS-transgene can be driven by any Gal4 line, this system is predominantly limited by available Gal4 lines. Here we report the characterization of a novel line, DE-Gal4, which in the eye is expressed in the dorsal compartment for the majority of development. Furthermore, we use functional tests to show that the DE-Gal4 line is a useful tool with which to manipulate gene expression in half of the developing eye.
ISSN: 1526-954X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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