Prasugrel versus clopidogrel for acute coronary syndromes without revascularization

Roe, Matthew T; Armstrong, Paul W; Fox, Keith AA; White, Harvey D; Prabhakaran, Dorairaj; Goodman, Shaun G; Cornel, Jan H; Bhatt, Deepak L; Clemmensen, Peter; Martinez, Felipe; Ardissino, Diego; Nicolau, Jose C; Boden, William E; Gurbel, Paul A; Ruzyllo, Witold; Dalby, Anthony J; McGuire, Darren K; Leiva-Pons, Jose L; Parkhomenko, Alexander; Gottlieb, Shmuel; Topacio, Gracita O; Hamm, Christian; Pavlides, Gregory; Goudev, Assen R; Oto, Ali; Tseng, Chuen-Den; Merkely, Bela; Gasparovic, Vladimir; Corbalan, Ramon; Cinteză, Mircea; McLendon, R Craig; Winters, Kenneth J; Brown, Eileen B; Lokhnygina, Yuliya; Aylward, Philip E; Huber, Kurt; Hochman, Judith S; Ohman, E Magnus; TRILOGY ACS Investigators,

doi:10.1056/NEJMoa1205512

Prasugrel versus clopidogrel for acute coronary syndromes without revascularization

Author:

Roe, Matthew T

Armstrong, Paul W ; Fox, Keith AA ; White, Harvey D ; Prabhakaran, Dorairaj ; Goodman, Shaun G ; Cornel, Jan H ; Bhatt, Deepak L ; Clemmensen, Peter ; Martinez, Felipe ; Ardissino, Diego ; Nicolau, Jose C ; Boden, William E ; Gurbel, Paul A ; Ruzyllo, Witold ; Dalby, Anthony J ; McGuire, Darren K ; Leiva-Pons, Jose L ; Parkhomenko, Alexander ; Gottlieb, Shmuel ; Topacio, Gracita O ; Hamm, Christian ; Pavlides, Gregory ; Goudev, Assen R ; Oto, Ali ; Tseng, Chuen-Den ; Merkely, Bela ; Gasparovic, Vladimir ; Corbalan, Ramon ; Cinteză, Mircea ; McLendon, R Craig ; Winters, Kenneth J ; Brown, Eileen B ; Lokhnygina, Yuliya ; Aylward, Philip E ; Huber, Kurt ; Hochman, Judith S ; Ohman, E Magnus ; TRILOGY ACS Investigators,

Keywords:

Acute Coronary Syndrome, Aged, Angina, Unstable, Aspirin, Cardiovascular Diseases, Double-Blind Method, Drug Therapy, Combination, Female, Follow-Up Studies, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Myocardial Infarction, Piperazines, Platelet Aggregation Inhibitors, Purinergic P2 Receptor Antagonists, Stroke, Thiophenes, Ticlopidine, Science & Technology, Life Sciences & Biomedicine, Medicine, General & Internal, General & Internal Medicine, MYOCARDIAL-INFARCTION, MEDICAL-MANAGEMENT, OUTCOMES, PREDICTORS, STRATEGY, Clopidogrel, Prasugrel Hydrochloride, TRILOGY ACS Investigators, 11 Medical and Health Sciences, 32 Biomedical and clinical sciences, 42 Health sciences

Abstract:

The effect of intensified platelet inhibition for patients with unstable angina or myocardial infarction without ST-segment elevation who do not undergo revascularization has not been delineated.