Title: Antithrombotic Therapy in Patients with Heart Valve Prostheses
Authors: Hermans, Hadewich ×
Vanassche, Thomas
Herijgers, Paul
Meuris, Bart
Herregods, Marie-Christine
Van de Werf, Frans
Verhamme, Peter #
Issue Date: 2013
Series Title: Cardiology in Review vol:21 issue:1 pages:27-36
Article number: 10.1097/CRD.0b013e3182638578
Abstract: Heart valve prostheses carry a risk for thrombosis and require an antithrombotic strategy to prevent stroke, systemic embolism, and prosthetic valve thrombosis. Contemporary randomized trials to guide the clinician on the optimal anticoagulant treatment are scarce, and the validity of the historical data for current recommendations can be questioned in view of the changes in valve prostheses, the patient population, and antithrombotic therapies. This limited evidence from clinical trials translates into divergent recommendations from the different scientific societies on the optimal intensity of oral anticoagulation and on the indication for antiplatelet therapy. The availability of new antithrombotic agents and the unclear thrombotic risk of the currently used prostheses underscore the need to redefine antithrombotic treatment in patients with heart valve prostheses.
ISSN: 1061-5377
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Department of Health and Technology - UC Leuven
Cardiac Surgery
Molecular and Vascular Biology
Experimental Cardiac Surgery (-)
× corresponding author
# (joint) last author

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