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Title: Complete Genome Sequence of the Novel Escherichia coli Phage phAPEC8
Authors: Tsonos, Jessica
Adriaenssens, Evelien
Klumpp, J
Hernalsteens, J-P
Lavigne, Rob ×
De Greve, Henri #
Issue Date: Dec-2012
Publisher: American Society for Microbiology (ASM)
Series Title: Journal of Virology vol:86 issue:23 pages:13117-8
Article number: 10.1128/JVI.02374-12
Abstract: Bacteriophage phAPEC8 is an Escherichia coli-infecting myovirus, isolated on an avian pathogenic Escherichia coli (APEC) strain. APEC strains cause colibacillosis in poultry, resulting in high mortality levels and important economic losses. Genomic analysis of the 147,737-bp double-stranded DNA phAPEC8 genome revealed that 53% of the 269 encoded proteins are unique to this phage. Its closest relatives include the Salmonella phage PVP-SE1 and the coliphage rv5, with 19% and 18% similar proteins, respectively. As such, phAPEC8 represents a novel, phylogenetically distinct clade within the Myoviridae, with molecular properties suitable for phage therapy applications.
URI: 
ISSN: 0022-538X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Division of Gene Technology
× corresponding author
# (joint) last author

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