Responsiveness to metformin in girls with androgen excess: collective influence of genetic polymorphisms
Díaz, Marta × López-Bermejo, Abel Sánchez-Infantes, David Bassols, Judit de Zegher, Francis Ibáñez, Lourdes #
American Society for Reproductive Medicine
Fertility and Sterility vol:96 issue:1 pages:208-213.e2
To study the relationship between the responsiveness to metformin in girls with androgen excess and combinations of genetic variants-as reflected in a polymorphism score-in single nucleotide polymorphisms (OCT1, STK11, and FTO genes) and in the repeat numbers within the AR and SHBG genes.