Carotid intima-media thickness at 7 years of age: relationship to C-reactive protein rather than adiposity
Osiniri, Inés × Sitjar, Carmen Soriano-Rodríguez, Pilar Prats-Puig, Anna Casas-Satre, Cristina Mayol, Lluís de Zegher, Francis Ibánez, Lourdes Bassols, Judit López-Bermejo, Abel #
Journal of Pediatrics vol:160 issue:2 pages:276-280.e1
According to the concept of adipose tissue expandability, the vascular complications of obesity are related less to the amount of stored fat than to the low-grade inflammation that excess fat storage may elicit. We tested this concept in 7-year-old children by assessing whether carotid intima-media thickness (cIMT) is related to obesity measures or to circulating highly sensitive C-reactive protein (hsCRP), as a marker of low-grade inflammation.