Soluble fatty acid synthase relates to bone biomarkers in prepubertal children
Prats-Puig, A × Puig, T Sitjar, C Mas-Parareda, M Grau-Cabrera, P Soriano-Rodríguez, P Montesinos-Costa, M Diaz, Claudia de Zegher, Francis Ibáñez, L Bassols, J López-Bermejo, A #
Osteoporosis International vol:23 issue:7 pages:2053-8
Circulating soluble fatty acid synthase (FASN, a key enzyme in de novo biosynthesis of fatty acids, expressed in both adipocytes and osteoblasts) is clinically related to a less favorable bone profile in healthy prepubertal children. Soluble FASN may participate in the reciprocal regulation between fat and bone metabolism.