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Title: Tadalafil monotherapy and as add-on to background bosentan in patients with pulmonary arterial hypertension
Authors: Barst, Robyn J ×
Oudiz, Ronald J
Beardsworth, Anthony
Brundage, Bruce H
Simonneau, Gerald
Ghofrani, Hossein A
Sundin, David P
Galiè, Nazzareno
Pulmonary Arterial Hypertension and Response to Tadalafil (PHIRST) Study Group #
Contributors: Delcroix, Marion
Issue Date: Jun-2011
Publisher: Mosby-Year Book
Series Title: Journal of Heart and Lung Transplantation vol:30 issue:6 pages:632-43
Abstract: Tadalafil 40 mg orally once daily, was shown to be well-tolerated and efficacious for pulmonary arterial hypertension in a 16-week, double-blind, placebo (PBO)-controlled trial. Inclusion criteria included the option for background bosentan. Analyses of tadalafil in treatment-naive patients and as add-on to bosentan were pre-specified. Objectives were to provide safety and efficacy data for both groups.
URI: 
ISSN: 1053-2498
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Pneumology
× corresponding author
# (joint) last author

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