Title: Tadalafil therapy for pulmonary arterial hypertension
Authors: Galiè, Nazzareno ×
Brundage, Bruce H
Ghofrani, Hossein A
Oudiz, Ronald J
Simonneau, Gerald
Safdar, Zeenat
Shapiro, Shelley
White, R James
Chan, Melanie
Beardsworth, Anthony
Frumkin, Lyn
Barst, Robyn J
Pulmonary Arterial Hypertension and Response to Tadalafil (PHIRST) Study Group #
Contributors: Delcroix, Marion
Issue Date: Jun-2009
Publisher: Lippincott Williams & Wilkins
Series Title: Circulation vol:119 issue:22 pages:2894-U65
Abstract: Treatment options for pulmonary arterial hypertension target the prostacyclin, endothelin, or nitric oxide pathways. Tadalafil, a phosphodiesterase type-5 inhibitor, increases cGMP, the final mediator in the nitric oxide pathway.
ISSN: 0009-7322
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Pneumology
× corresponding author
# (joint) last author

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