Carpal tunnel syndrome and musculoskeletal symptoms in postmenopausal women with early breast cancer treated with exemestane or tamoxifen after 2-3 years of tamoxifen: a retrospective analysis of the Intergroup Exemestane Study
Mieog, J Sven D × Morden, James P Bliss, Judith M Coombes, R Charles van de Velde, Cornelis J H IES Steering Committee Paridaens, Robert #
Lancet Pub. Group
The Lancet Oncology vol:13 issue:4 pages:420-432
Aromatase inhibitors are more effective than is tamoxifen in prevention of breast-cancer recurrence, but at the expense of increased musculoskeletal side-effects, such as carpal tunnel syndrome. The aim of this study was to assess risk factors and the prognostic value of musculoskeletal symptoms during treatment with the steroidal aromatase inhibitor exemestane or with tamoxifen after 2-3 years of tamoxifen.