Hyaluronic acid for the treatment of osteoarthritis in all joints except the knee: what is the current evidence?
Colen, Sascha × Haverkamp, Daniel Mulier, Michiel van den Bekerom, Michel P J #
BioDrugs vol:26 issue:2 pages:101-112
The use of intra-articular hyaluronic acid (HA) is a well known treatment in patients with knee osteoarthritis (OA). In other joints, less evidence is available about the efficacy of treatment with intra-articular HA. HA is also used intra-articularly in the metatarsophalangeal-1 joint, the ankle, the hip, the sacroiliac joint, the facet joints, the carpometacarpal-1 joint, the shoulder and the temporo-mandibular joint. In this systematic review we include all prospective studies about the effects of intra-articular HA in the above-mentioned joints. Its use in the knee joint, however, will be discussed in a separate article in this journal.