Impact of clinical fractures on health-related quality of life is dependent on time of assessment since fracture: results from the FREEDOM trial
Silverman, S × Viswanathan, H N Yang, Y-C Wang, A Boonen, Steven Ragi-Eis, S Fardellone, P Gilchrist, N Lips, P Nevitt, M Palacios Gil-Antuñano, S Pavelka, K Revicki, D Simon, Jean-Pierre Macarios, D Siris, E S #
Osteoporosis International vol:23 issue:4 pages:1361-9
In the Fracture Reduction Evaluation of Denosumab in Osteoporosis Every 6 Months (FREEDOM) study, women with incident clinical fractures reported significant declines in health-related quality of life (HRQoL). The largest declines were observed when the assessment was <3 months post fracture. The largest impact of incident clinical fractures was on physical function, and that of incident clinical vertebral fractures was on back pain.