Title: Recommendations for the treatment of epilepsy in adult patients in general practice in Belgium: an update
Authors: Boon, Paul ×
Engelborghs, Sebastiaan
Hauman, Henri
Jansen, An
Lagae, Lieven
Legros, Benjamin
Ossemann, Michel
Sadzot, Bernard
Smets, Katrien
Urbain, Etienne
van Rijckevorsel, Kenou #
Issue Date: Jun-2012
Publisher: Acta Medica Belgica
Series Title: Acta Neurologica Belgica vol:112 issue:2 pages:119-131
Abstract: In 2008, a group of Belgian epilepsy experts published recommendations for antiepileptic drug (AED) treatment of epilepsies in adults and children. Selection of compounds was based on the registration and reimbursement status in Belgium, the level of evidence for efficacy, common daily practice and the personal views and experiences of the authors. In November 2011 the validity of these recommendations was reviewed by the same group of Belgian epilepsy experts who contributed to the preparation of the original paper. The recommendations made in 2008 for initial monotherapy in paediatric patients were still considered to be valid, except for the first choice treatment for childhood absence epilepsy. This update therefore focuses on the treatment recommendations for initial monotherapy and add-on treatment in adult patients. Several other relevant aspects of treatment with AEDs are addressed, including considerations for optimal combination of AEDs (rational polytherapy), pharmacokinetic properties, pharmacodynamic and pharmacokinetic interaction profile, adverse effects, comorbidity, treatment of elderly patients, AED treatment during pregnancy, and generic substitution of AEDs.
ISSN: 0300-9009
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Neuro-musculo-skeletal Research (-)
Clerkships Office, Faculty of Medicine - miscellaneous
× corresponding author
# (joint) last author

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