Both Paecilomyces spp. and Alternaria spp. are hyphomycetes with a worldwide distribution, and with many species being common saprophytes in soil and air. Both species mainly cause infections in immunocompromised patients, but also in an increasing number of immunocompetent hosts. We describe a double-lung transplant patient suffering successively from two rare cutaneous fungal infections caused by Paecilomyces lilacinus and Alternaria infectoria. Antifungal treatment and surgery of residual skin lesions was necessary to cure the infections. With this report, we aim at highlighting the importance of dermatological control of patients post lung transplantation.