Title: The bicyclam AMD3100 story
Authors: De Clercq, Erik # ×
Issue Date: Jul-2003
Series Title: Nature reviews. Drug discovery vol:2 issue:7 pages:581-7
Abstract: The discovery and development of the bicyclam AMD3100--a chemokine receptor antagonist--has highlighted the therapeutic potential of such compounds in HIV infection, inflammatory diseases, cancer and stem-cell mobilization. Here, I describe the development process of AMD3100, which began about 15 years ago with the isolation of an impurity, and the basis for the clinical application of AMD3100 and its congeners.
ISSN: 1474-1776
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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