Title: Bicyclic anti-VZV nucleosides: thieno analogues bearing an alkylphenyl side chain have reduced antiviral activity
Authors: Angell, Annette ×
McGuigan, Christopher
Garcia Sevillano, Luis
Snoeck, Robert
Andrei, Graciela
De Clercq, Erik
Balzarini, Jan #
Issue Date: May-2004
Series Title: Bioorganic & medicinal chemistry letters vol:14 issue:10 pages:2397-9
Abstract: Thieno analogues of the potent and selective furo-pyrimidine anti-VZV nucleoside family bearing a p-alkylphenyl side chain have been synthesised and tested for their antiviral activity against Varicella-Zoster virus (VZV). While the alkyl chain analogues were shown to retain full antiviral activity against VZV, these new analogues did not when compared to their furo parent nucleosides.
ISSN: 0960-894X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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