Comprehensive mutation analysis in colorectal flat adenomas
Voorham, Quirinus J M × Carvalho, Beatriz Spiertz, Angela J Claes, Bart Mongera, Sandra van Grieken, Nicole C T Grabsch, Heike Kliment, Martin Rembacken, Bjorn van de Wiel, Mark A Quirke, Philip Mulder, Chris J J Lambrechts, Diether van Engeland, Manon Meijer, Gerrit A #
Public Library of Sciene
PLoS One vol:7 issue:7 pages:e41963-e41963
Flat adenomas are a subgroup of colorectal adenomas that have been associated with a distinct biology and a more aggressive clinical behavior compared to their polypoid counterparts. In the present study, we aimed to compare the mutation spectrum of 14 cancer genes, between these two phenotypes.