Title: SlidingBayes: exploring recombination using a sliding window approach based on Bayesian phylogenetic inference
Authors: Paraskevis, D ×
Deforche, Koen
Lemey, Philippe
Magiorkinis, G
Hatzakis, A
Vandamme, Anne-Mieke #
Issue Date: Apr-2005
Publisher: Oxford University Press
Series Title: Bioinformatics vol:21 issue:7 pages:1274-1275
Abstract: We developed a software tool (SlidingBayes) for recombination analysis based on Bayesian phylogenetic inference. Sliding-Bayes provides a powerful approach for detecting potential recombination, especially between highly divergent sequences and complex HIV-1 recombinants for which simpler methods like neighbor joining (NJ) may be less powerful. SlidingBayes guides Markov Chain Monte Carlo (MCMC) sampling performed by MrBayes in a sliding window across the alignment (Bayesian scanning). The tool can be used for nucleotide and amino acid sequences and combines all the modeling possibilities of MrBayes with the ability to plot the posterior probability support for clustering of various combinations of taxa.
ISSN: 1367-4803
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Clinical and Epidemiological Virology (Rega Institute)
× corresponding author
# (joint) last author

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