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Title: Post-therapeutic surveillance strategies in head and neck squamous cell carcinoma
Authors: Digonnet, Antoine ×
Hamoir, Marc
Andry, Guy
Haigentz, Missak
Takes, Robert
Silver, Carl
Hartl, Dana
Strojan, Primoz
Rinaldo, Alessandra
De Bree, Remco
Dietz, Andreas
Grégoire, Vincent
Paleri, Vinidh
Langendijk, Johannes
Vander Poorten, Vincent
Hinni, Michael
Rodrigo, Juan
Suarez, Carlos
Mendenhall, William
Werner, Jochen
Genden, Eric
Ferlito, Alfio #
Issue Date: 13-Sep-2012
Publisher: Springer-Verlag
Series Title: Springer Tracts in Modern Physics
Abstract: The management of head and neck squamous cell carcinomas does not end with the completion of ablative therapy. The oncologic objectives of post-treatment follow-up are to detect recurrences and second primary tumors; beyond that, follow-up should evaluate acute and chronic treatment-related side effects, guide the rehabilitation process, alleviate functional loss, manage pain, restore nutritional status and assess psychosocial factors. In this structured review, we address the questions of timing and the tools required to achieve a complete and coherent routine surveillance. Several guidelines and consensus statements recommend clinical examination as the cornerstone of follow-up which should be performed for at least 5 years, although there are no data in favor of any one particular follow-up program, and only low-level evidence suggests an improvement in oncologic outcomes by close follow-up. Baseline imaging (computed tomography and magnetic resonance imaging) should be obtained within 2-6 months after definitive therapy if used for treatment response evaluation. Metabolic response, if indicated, should be assessed preferably after 3 months in patients who undergo curative-intent therapy with (chemo)-radiotherapy. Chest computed tomography is more sensitive than plain radiography, if used in follow-up, but the benefit and cost-effectiveness of routine chest computed tomography has not been demonstrated. There are no current data supporting modifications specific to the surveillance plan of patients with human papillomavirus-associated disease.
ISSN: 0081-3869
Publication status: accepted
KU Leuven publication type: IT
Appears in Collections:Head and Neck Oncology (+)
× corresponding author
# (joint) last author

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