Head and Neck Cancer Imaging edition:2 pages:387-407
Wider availability of and technical improvements in anatomic and biological imaging have facilitated the implementation of high-precision three-dimensional conformal and intensity-modulated radiotherapy (RT) in head and neck cancer. The integration of recent advances in functional and molecular imaging have already improved staging, RT delivery, response prediction, and follow-up. Rational clinical use of all modalities should be encouraged, especially in the setting of imaging-intensive investigational RT protocols such as adaptive therapy. Expanded development of imaging markers which can predict radioresistance or outcome could further customize treatment. Continued successful use of innovative imaging in routine clinical practice will ultimately depend on well-designed clinical studies with adequate follow-up.