Comparison of serum testosterone and estradiol measurements in 3174 European men using platform immunoassay and mass spectrometry; relevance for the diagnostics in aging men
Huhtaniemi, Ilpo T × Tajar, Abdelouahid Lee, David M O'Neill, Terence W Finn, Joseph D Bartfai, György Boonen, Steven Casanueva, Felipe F Giwercman, Aleksander Kula, Krzysztof Labrie, Fernand Lean, Michael E J Pendleton, Neil Punab, Margus Silman, Alan J Vanderschueren, Dirk Forti, Gianni Wu, Frederick C W EMAS Group #
European Journal of Endocrinology vol:166 issue:6 pages:983-991
The limitations of serum testosterone and estradiol (E(2)) measurements using non-extraction platform immunoassays (IAs) are widely recognized. Switching to more specific mass spectrometry (MS)-based methods has been advocated, but directly comparative data on the two methods are scarce.