Title: Matricellular signaling molecule CCN1 attenuates experimental autoimmune myocarditis by acting as a novel immune cell migration modulator
Authors: Rother, Madlen *
Krohn, Stefanie *
Kania, Gabriela
Vanhoutte, Davy
Eisenreich, Andreas
Wang, Xiaomin
Westermann, Dirk
Savvatis, Kostas
Dannemann, Nadine
Skurk, Carsten
Hilfiker-Kleiner, Denise
Cathomen, Toni
Fechner, Henry
Rauch, Ursula
Schultheiss, Heinz-Peter
Heymans, Stephane
Eriksson, Urs
Scheibenbogen, Carmen
Poller, Wolfgang # ×
Issue Date: Dec-2010
Publisher: Lippincott Williams & Wilkins
Series Title: Circulation vol:122 issue:25 pages:2688-98
Abstract: CCN1 is an evolutionary ancient matricellular protein that modulates biological processes associated with tissue repair. Induction at sites of injury was observed in conditions ranging from skin wounds to cardiac diseases, including ischemic and inflammatory cardiomyopathy. Here, we provide evidence of a novel function of CCN1 as a modulator of immune cell migration.
ISSN: 0009-7322
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Cardiology
* (joint) first author
× corresponding author
# (joint) last author

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