Concomitant hyperthermia and radiation therapy for treating locally advanced rectal cancer
De Haas-Kock, Danielle F M × Buijsen, Jeroen Pijls-Johannesma, Madelon Lutgens, Ludy Lammering, Guido van Mastrigt, Ghislaine A P G De Ruysscher, Dirk Lambin, Philippe van der Zee, Jacoba #
Cochrane Database of Systematic Reviews issue:3
Surgery has been the treatment of choice for patients with rectal cancer. For locally advanced cancer results were poor, with high rates of locoregional recurrences and poor overall survival data. Adding (chemo)radiotherapy upfront improved results mainly in locoregional control. Adding hyperthermia to radiotherapy preoperatively might have an equivalent beneficial effect.