Combined use of hyperthermia and radiation therapy for treating locally advanced cervical carcinoma
Lutgens, Ludy van der Zee, Jacoba Pijls-Johannesma, Madelon De Haas-Kock, Danielle Fm Buijsen, Jeroen Mastrigt, Ghislaine Apg van Lammering, Guido De Ruysscher, Dirk Lambin, Philippe
Cochrane Database of Systematic Reviews issue:1
Hyperthermia is a type of cancer treatment in which body tissue is exposed to high temperatures to damage and kill cancer cells. It was introduced into clinical oncology practice several decades ago. Positive clinical results, mostly obtained in single institutions, resulted in clinical implementation albeit in a limited number of cancer centres worldwide. Because large scale randomised clinical trials (RCTs) are lacking, firm conclusions cannot be drawn regarding its definitive role as an adjunct to radiotherapy in the treatment of locally advanced cervical carcinoma (LACC).