Title: Imidazothiadiazine dioxides: synthesis and antiviral activity
Authors: Martínez, A ×
Esteban, A I
Herrero, A
Ochoa, C
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik #
Issue Date: Aug-1999
Series Title: Bioorganic & medicinal chemistry vol:7 issue:8 pages:1617-23
Abstract: A new series of imidazothiadiazine dioxides, including the first acyclonucleosides derived from this heterocycle moiety, has been synthesized. A wide-spectrum antiviral screening was performed. Some of the N-1 benzyl imidazothiadiazines and the new acyclonucleosides showed interesting anti-CMV or anti-HIV activity. These structures could be considered as new lead compounds for antiviral drug research.
ISSN: 0968-0896
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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