Variations in target volume definition for postoperative radiotherapy in stage III non-small-cell lung cancer: analysis of an international contouring study
Spoelstra, Femke O. B × Senan, Suresh Le Pechoux, Cecile Ishikura, Satoshi Casas, Francesc Ball, David Price, Allan De Ruysscher, Dirk de Koste, John R. van Sornsen #
International Journal of Radiation Oncology, Biology, Physics vol:76 issue:4 pages:1106-1113
Purpose: Postoperative radiotherapy (PORT) in patients with completely resected non small-cell lung cancer with mediastinal involvement is controversial because of the failure of earlier trials to demonstrate a survival benefit. Improved techniques may reduce toxicity, but the treatment fields used in routine practice have not been well studied. We studied routine target volumes used by international experts and evaluated the impact of a contouring protocol developed for a new prospective study, the Lung Adjuvant Radiotherapy Trial (Lung ART).