18F-Fluorodeoxyglucose uptake patterns in lung before radiotherapy identify areas more susceptible to radiation-induced lung toxicity in non-small-cell lung cancer patients
Petit, Steven F × van Elmpt, Wouter J. C Oberije, Cary J. G Vegt, Erik Dingemans, Anne-Marie C Lambin, Philippe Dekker, Andre L. A. J De Ruysscher, Dirk #
International Journal of Radiation Oncology, Biology, Physics vol:81 issue:3 pages:698-705
Purpose: Our hypothesis was that pretreatment inflammation in the lung makes pulmonary tissue more susceptible to radiation damage. The relationship between pretreatment [F-18]fluorodeoxyglucose ([F-18]FDG) uptake in the lungs (as a surrogate for inflammation) and the delivered radiation dose and radiation-induced lung toxicity (RILT) was investigated.