Volume or position changes of primary lung tumor during (chemo-)radiotherapy cannot be used as a surrogate for mediastinal lymph node changes: the case for optimal mediastinal lymph node imaging during radiotherapy
van Elmpt, Wouter × Ollers, Michel van Herwijnen, Henrieke den Holder, Linda Vercoulen, Lindsay Wouters, Monique Lambin, Philippe De Ruysscher, Dirk #
International Journal of Radiation Oncology, Biology, Physics vol:79 issue:1 pages:89-95
Purpose: Primary lung tumors can he visualized mostly with cone beam computed tomography (CT), whereas visualization is much more difficult for mediastinal lymph nodes (LN). If the volumetric and positional changes of the primary tumor could be used as a surrogate for the LN, this would facilitate image-guided radiotherapy. The purpose of this study was to investigate the relationship between the positional and volumetric changes in primary tumors and the involved LN during (chemo)radiotherapy treatment of non-small-cell lung cancer patients.