Title: The Use of FDG-PET to Target Tumors by Radiotherapy
Authors: Lammering, Guido ×
De Ruysscher, Dirk
van Baardwijk, Angela
Baumert, Brigitta G
Borger, Jacques
Lutgens, Ludy
van den Ende, Piet
Ollers, Michel
Lambin, Philippe #
Issue Date: Sep-2010
Publisher: Urban & Vogel
Series Title: Strahlentherapie und Onkologie vol:186 issue:9 pages:471-481
Abstract: Fluorodeoxyglucose positron emission tomography (FDG-PET) plays an increasingly important role in radiotherapy, beyond staging and selection of patients. Especially for non-small cell lung cancer, FDG-PET has, in the majority of the patients, led to the safe decrease of radiotherapy volumes, enabling radiation dose escalation and, experimentally, redistribution of radiation doses within the tumor. In limited-disease small cell lung cancer, the role of FDG-PET is emerging. For primary brain tumors, PET based on amino acid tracers is currently the best choice, including high-grade glioma. This is especially true for low-grade gliomas, where most data are available for the use of C-11-MET (methionine) in radiation treatment planning. For esophageal cancer, the main advantage of FOG-PET is the detection of otherwise unrecognized lymph node metastases. In Hodgkin's disease, FDG-PET is essential for involved-node irradiation and leads to decreased irradiation volumes while also decreasing geographic miss. FDG-PET's major role in the treatment of cervical cancer with radiation lies in the detection of para-aortic nodes that can be encompassed in radiation fields. Besides for staging purposes, FDG-PET is not recommended for routine radiotherapy delineation purposes. It should be emphasized that using PET is only safe when adhering to strictly standardized protocols.
ISSN: 0179-7158
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Department of Oncology - miscellaneous
Laboratory of Experimental Radiotherapy
× corresponding author
# (joint) last author

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