Title: PET imaging of hypoxia using [F-18]HX4: a phase I trial
Authors: van Loon, Judith ×
Janssen, Marco H. M
Ollers, Michel
Aerts, Hugo J. W. L
Dubois, Ludwig
Hochstenbag, Monique
Dingemans, Anne-Marie C
Lalisang, Roy
Brans, Boudewijn
Windhorst, Bert
van Dongen, Guus A
Kolb, Hartmuth
Zhang, James
De Ruysscher, Dirk
Lambin, Philippe #
Issue Date: Aug-2010
Series Title: European Journal of Nuclear Medicine and Molecular Imaging vol:37 issue:9 pages:1663-1668
Abstract: Noninvasive PET imaging of tumour hypoxia could help in the selection of those patients who could benefit from chemotherapy or radiation with specific antihypoxic treatments such as bioreductive drugs or hypoxic radiosensitizers. In this phase I trial, we aimed to determine the toxicity of [F-18]HX4, a member of the 2-nitroimidazole family, at different dose levels. The secondary aim was to analyse image quality related to the HX4 dose and the timing of imaging.
ISSN: 1619-7070
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Department of Oncology - miscellaneous
Laboratory of Experimental Radiotherapy
Laboratory of Molecular Bacteriology (Rega Institute)
× corresponding author
# (joint) last author

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